300 tab gelatin candy mold12/5/2023 Multiple Compressed Tablets/ Multi-compressed Tablets Gelatin-coated tablets are also ideal for double-blind clinical studies, or for drug substances that can irritate the oesophagal mucosa when they are incorporated in an immediate-release tablet such as bisphosphonates.Įxample of gelatin-coated tablets includes gelatin-coated hydrochlorothiazide tablet (Qualitest Pharmaceuticals), Tylenol Cold Multi-Symptom Daytime (McNeil Consumer) etc. The gelatin coating also facilitates swallowing, enables custom branding, and prevents counterfeit since they are more tamper-evident than unsealed capsules. The gelatin coating impacts the same general characteristics as sugar coating and film coating with the added advantage of improving the stability of photosensitive APIs. Gelatin-coated tablets are compressed tablets coated with either one or two-toned colour gelatin. ![]() Examples include silver potentiate, bichloride of mercury merbromin and quaternary ammonium compounds. ![]() These tablets contain large amounts of highly potent APIs, and thus are used by a pharmacist to compound prescriptions that can be incorporated readily into powders and liquids, thus, circumventing the necessity to weigh small quantities of these potent drug substances.ĭispensing tablets are no longer in use and had the dangerous potential of being inadvertently dispensed as such to patients. Dispensing Tabletsĭispensing tablets also referred to as compounding tablets are tablets supplied primarily as a convenience for extemporaneous compounding. e.g., Dilaudid – Dihydromorphinone HCl (Bilhuber Knoll Corp.). Also, the availability of stable parenteral solutions and prefabricated injectable products, some in disposable syringes have also discouraged their use in recent times. Hypodermic tablets are no longer used in most countries due to the difficulty in achieving sterility. These tablets are dissolved in a suitable vehicle (water for injections) and administered by parenteral route. Hypodermic tablets are soft, readily soluble tablets that were originally used by physicians in extemporaneous preparation of parenteral solutions. A typical example of tablet triturate is NTG tablets. One of the problems encountered during the manufacture of this tablet type is the failure to find a lubricant that is completely water-soluble. ![]() Since tablet triturates must completely and rapidly dissolve in water, only a minimal amount of pressure is applied during their manufacture. They are prepared from moist material, using a triturate mould that gives them the shape of cut sections of a cylinder. Tablet triturates are small, usually cylindrical, moulded, or compressed tablets containing small amounts of usually potent drugs mixed with a combination of sucrose and lactose or any suitable diluent. They are intended to be slowly dissolved in the oral cavity, usually for local effects.Įxamples include Strepsils Dry Cough Lozenges – Dextromethorphan Hydrobromide 5mg, Dichlorobenzyl alcohol 1.2mg, Amylmetacresol 0.6mg (Reckitt Benckiser), Dequadine – Dequalinium chloride BP 250mcg (Evans Medical PLC), Dr Meyer Coflin cough lozenges (Meyer Organics PVT Ltd), Cofta – Ammonium chloride/ Ipecacuanha tablet (Evans Medical PLC) etc. These are disc-shaped solid preparations containing medicinal agents and generally a flavouring substance in a hard candy or sugar base.
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